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Originally Posted by Michaelangelica
“Humans appear to have lost what may have been a natural resistance to HIV some 7 million years when our bodies stopped producing particular kinds of protein
These circular proteins, called cyclotides
The first cyclotide discovered in mammals, RTD1, was found in rhesus monkeys and when chemically synthesised acts against HIV.
Cyclotides are found in herbs:
http://www.cyclotide.com/
“Cyclotides have a range of interesting biological activities including anti-HIV and neurotensin inhibition, anti-microbial activity and insecticidal activity. They are found in a variety of tropical plants from the Rubiaceae and Violaceae families.”
Does this mean that herbs with cyclotides such as Violet, Heartsease , Inkweed and Soapwort would be good for HIV?
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That is cool information Michealangelica.
I think it could be an answer??
Perhaps cyclotides can disrupt the HIV enzymes protease and integrase.
Whether it could "cure" HIV or merely offer an alternative lifetime treatment is a $Multi-Billion dollar question??
HIV quickly mutates and rapidly develops resistance.
fight fire with fire>>> Protein with protein??
Plants are pretty amazing. Which is why we need to stop species from disappearing before we know what potentials they may hold.
I don't know enough about cyclotides at this time, but thanks for the links!