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Re: Anti-Viral Plants

From: http://www.ars-grin.gov/cgi-bin/duke/farmacy-scroll3.pl

I dont really understand any of the below, but it is probably pretty interesting to people who do...

__________________________________________________ ____
Chemicals and their Biological Activities in: Syzgium claviflorum ()

Chemicals

BETULINIC-ACID Leaf: JAD

Anthelmintic X11315752 ; Antibacterial X10630117 ; Anticancer JBH ; Anticarcinomic JBH ; Antiedemic X7701004 ; AntiHIV 14.8 uM EC50=2.0 ug/ml JNP61:1090 IC50=6.5 ug/ml; Antiinflammatory PM61:9 ; Antileukemic X9353895 ; Antimalarial IC50=19-26 ug/ml PR13:115 ; Antimelanomic NYT3/28/95 ; Antinociceptive; Antiplasmodial PR13:115 ; Antitumor JBH ; Antiviral 14.8 uM; Apoptotic; Cytotoxic 16.4 uM JNP66:263 50-100 ppm BPCC ; Phospholipase-A2-Inhibitor X11684183 ; Prostaglandin-Synthesis-Inhibitor 200 ug/ml PC48:495 IC50=101 uM YHH30:621

__________________________________________________ _____

BETULINIC-ACID
Biological Activities

Anthelmintic Reference: X11315752
AntiHIV Dosage: IC50=6.5 ug/ml; Reference: JNP61:1090 JNP57:243 Dosage: EC50=2.0 ug/ml; Reference: JNP61:1090 Dosage: 14.8 uM; Reference: JNP66:263 JNP57:243
Antibacterial Reference: X10630117
Anticancer Reference: JBH
Anticarcinomic Reference: JBH
Antiedemic Reference: X7701004
Antiinflammatory Reference: PM61:9
Antileukemic Reference: X9353895
Antimalarial Dosage: IC50=19-26 ug/ml; Reference: PR13:115
Antimelanomic Reference: NYT3/28/95
Antinociceptive Reference: 1; X103991940
Antiplasmodial Dosage: IC50=19-26 ug/ml; Reference: PR13:115
Antitumor Reference: JBH
Antiviral Dosage: 14.8 uM; Reference: JNP66:263 JNP57:243
Apoptotic Reference: X11107130 X7489361
Cytotoxic Dosage: 50-100 ppm; Reference: BPCC Dosage: 16.4 uM; Reference: JNP66:263
Phospholipase-A2-Inhibitor Reference: X11684183
Prostaglandin-Synthesis-Inhibitor Dosage: 200 ug/ml; Reference: PC48:495 Dosage: IC50=101 uM; Reference: YHH30:621

Plant species with highest amount

Psophocarpus tetragonolobus (L.) DC. -- Asparagus Pea, Goa Bean, Winged Bean; 53,000 ppm in Root JAD;
Diospyros perigrina; 25,000 - 30,000 ppm in Bark PHYT13:2002 JAD;
Solanum aviculare; 30,000 ppm in Tissue Culture JAD;
Wormia burbidgei; 24,000 ppm in Bark PHYT13:2002 JAD;
Arbutus menziesii PURSH.; 20,000 ppm in Plant JAD; 20,000 ppm in Plant PHYT13:2002;
Cornus florida L. -- American Dogwood; 20,000 ppm in Bark JAD; 20,000 ppm in Bark PHYT13:2002;
Lemaireocereus griseus; 20,000 ppm in Plant PHYT13:2002 JAD;
Ternstromia merriliana JACK.; 20,000 ppm in Bark PHYT13:2002 JAD;
Dillenia indica L.; 19,000 ppm in Pericarp JAD;
Eurya acuminata DC; 18,000 ppm in Bark PHYT13:2002 JAD;
Platanus accrifolia WILLD.; 18,000 ppm in Bark PHYT13:2002;
Platanus acerifolia; 18,000 ppm in Bark JAD;
Platanus occidentalis L.; 17,500 ppm in Bark JAD;
Platanus orientalis L.; 17,500 ppm in Bark PHYT13:2002;
Nuytsia floribunda R.BR.; 17,000 ppm in Shoot PHYT13:2002 JAD;
Dillenia retusa THUNB.; 16,000 ppm in Fruit JAD;
Wormia triquetra ROTTB.; 16,000 ppm in Bark PHYT13:2002 JAD;
Diospyros montana; 15,300 ppm in Bark JAD;
Tetracera scandens; 13,500 ppm in Leaf JAD;
Dillenia indica L.; 13,000 ppm in Bark PHYT13:2002 JAD;
Tetracera sarmentosa; 12,300 ppm in Leaf JAD;
Spondianthus preussii; 12,000 ppm in Stem Bark JAD;
Syncarpia glomulifera; 12,000 ppm in Bark JAD;
Syncarpia laurifolia TENORE; 12,000 ppm in Bark PHYT13:2002 JAD;
Tetracera akara; 10,500 ppm in Leaf JAD;
Tectona grandis L.F -- Teak; 10,000 ppm in Wood PHYT13:2002 JAD;
Wormia triquetra ROTTB.; 10,000 ppm in Fruit PHYT13:2002 JAD;
Zizyphus jujuba MILL. -- Da-Zao, Jujube, Ta-Tsao; 10,000 ppm in Bark JAD;
Dillenia pentagyna; 9,800 ppm in Leaf JAD;
Alphitonia excelsa; 8,700 ppm in Leaf JAD;


__________________________________________________ ________

Chemicals with Antihiv Activity

(+)-CATECHIN EC50=4 ug/ml
AJOENE
ALPHITOLIC-ACID EC50=20 ug/ml IC50=4 ug/ml
AMENTOFLAVONE IC50=119 ug/ml IC97=200 ug/ml
APIGENIN IC50=143 ug/ml IC72=200 ug/ml
ARCTIGENIN IC65=0.27 uM IC85=0.5 uM
BAICALEIN
BAICALIN
BAICALIN-A
BETULIN 6.1 uM
BETULINIC-ACID 14.8 uM EC50=2.0 ug/ml IC50=6.5 ug/ml
CAFFEIC-ACID EC50=200 ug/ml
CARNOSOL
CARNOSOLIC-ACID IC90=0.32 ug/ml
CASTANOSPERMINE
CHICORIC-ACID
CHLOROGENIC-ACID
CHRYSIN
CICHORIC-ACID
COLCHICINE EC50=0.01 uM
CURCUMIN IC50=40 uM
DIALLYL-DISULFIDE
ELLAGIC-ACID IC90=200 ug/ml
ELLAGITANNIN
EPICATECHIN EC50=2 ug/ml
FULVOPLUMIERIN IC50=45 ug/ml
GALLIC-ACID
GERANIIN
GLYCYRRHISOFLAVONE
GLYCYRRHIZIN 0.6 mM
GOSSYPOL 100 uM
HINOKIFLAVONE IC50=62 ug/ml IC90=200 ug/ml
ISOLICOFLAVONOL 20 ug/ml
KAEMPFEROL-3-O-GLUCOSIDE
LICOCHALCONE-A 20 ug/ml
LIGNIN
LUTEOLIN
MASLINIC-ACID IC100=18 ug/ml
METHANOL EC50=<20 ug/ml
MYRICETIN
NARINGENIN IC35=200 ug/ml
OLEANOLIC-ACID EC50=1.7 ug/ml IC50=21.8 ug/ml
PAPAVERINE 10 ug/ml 900 mg/man/day/orl
POLYPHENOLS
POMOLIC-ACID EC50=1.4 ug/ml IC50=23.3 ug/ml
PROCYANIDIN
PROCYANIDINS
PUNICALAGIN
QUERCETAGETIN
QUERCETIN
ROSMARINIC-ACID EC50=40 ug/ml
TANNIC-ACID IC90=200 ug/ml
TANNIN
TILIROSIDE
TRACHELOGENIN IC65=0.52 uM
URSOLIC-ACID 6.7 uM EC50=2.0 ug/ml IC50=6.5 ug/ml IC85=18 ug/ml


----------------
Stephen Robert Irwin: 22 February 1962 – 4 September 2006. Rest In Peace.

Life is not a problem to be solved, it is a mystery to be lived. -Kierkegaard
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