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Re: electro-shock therapy
The new trend in psychiatry seems to be moving away from ECT, because the risks are seen to outweigh the benefits. Although I've also read about some people who failed to respond to any medication, but they responded very well to ECT.
A safer new alternative seems to be stimulation of the vagus nerve. It was initially used in the treatment of epilepsy, but studies have subsequently show that it is effective in the treatment of depression as well. This form of treatment doesn't seem to yield so many dangerous side effects.
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