[JulianKeller]

Hi

I have my own theories of how to make a Super Soldier and the Hulk, please help me iron them out. Thank you

Super Soldier Serum Hypothesis

I theorize to combine the chemicals that trigger anger, emotional detachment for intuitive pattern solving, the ability people have to 'slow time down' when it counts, and a little something to help the reflexes and inject them into a person for a while, while they have it in their system become the ultimate Supersoldier.


Hulk Hypothesis

Same thing except add adrenaline hormones so it triggers the Adrenal response and the General Adaption thing an also some green florescent protein with a hell of a lot of caffeine into the system.


I'm wondering how plausible this is because I flunked science in high school and didn't go to college. An is there a possible better answer (I know there has to be and that's what I'm fishing for) Better ways to create a supersoldier through possible genetic recombinant biotech and hell make him green and glowy too.

[freeztar]

Sure, you could make a serum out of things like adrenaline, testosterone, caffeine, etc. It would certainly boost the soldier's alertness/reaction time/endurance/etc., but it would not make them "super".

In the fictional movie "Jacob's Ladder", a platoon in Vietnam is administered a drug that causes them to go berserk. Unfortunately, they were so raving mad that they began to kill each other. Those that survived were haunted with flashbacks their whole lives. The reason I bring this up is to illustrate how boosting people's abilities, whether through serums or genetics, can have unforeseen, and sometimes tragic, consequences. I would certainly be wary of taking a "super serum", wouldn't you?

[Reaper]

These drugs already exist. They are called "steroids". All we have to do is solve the shrinking testicle problem, then I'm sure they will be much more widespread.

[GAHD]

A serum should only be taken once, no? Safe to say it would best be a biological agent, perhapse one or many engineered retrovirus' without the ability to create a new vireal sheath to reinfect other cells. (or alternately, don't and make it an ST"D")

something(s) designed to slide in and manipulate the human equivalents of the genes isolated in these experiments:

http://hypography.com/forums/medical...ow-organs.html
"SCIENTISTS have created a “miracle mouse” that can regenerate amputated limbs or badly damaged organs, making it able to recover from injuries that would kill or permanently disable normal animals."

http://hypography.com/forums/news-br...cientists.html
" The mouse can run up to six kilometres at a speed of 20 metres per minute for five hours or more without stopping,"

http://hypography.com/forums/medical...-mightier.html
"these muscular mice averaged a 117 percent increase in muscle fiber size and a 73 percent increase in total muscle fibers compared to normal mice." (seriously, look at the picture!)

They Have isolated the human genes for this last one atleast, the others I'm not so shure. weather they could breed a viri to target those specific parts for dislocation with modern research is another matter.

I'd like to see what the decendants of these 3 lines intermixed would be like!

For comic fan appeal, this would be more akin to the Greay Hulk: That much densely packed muscle offers a certain armor of it's own, but combined with regenerative capabilities, an allbut decapitated person has a chance to recover.

[Alighieri]

Hormones, including adrenaline and testosterone, though they clearly alter mood and metabolic functions, are constituents of the endocrine system which has the function of regulating homeostasis. As a result the hormones would cause both a feedback inhibition in the structures which naturally produce them as well as cause an increase production of antagonist hormones such as estrogen. The effects would thus be short lived and would probably result in undesirable side effects.

The introduction of a virus carrying specific genes is a very interesting alternative and would definently be permanent. The idea of embedding or proliferating new genes into humans via transduction is appears promising. That being said, it would need to be done cautiously due to potential dangers. Introduced genes that are not initially part of the genome can be repressed by pre-transcriptional editing mechanisms or RNA inhibition. If they do managed to be expressed, there is the possibility of mutating into an oncogene, which would not be good. Also steps would need to be taken to assure that the retrovirus becomes endogenous after infection, preventing further infection or a potential immune response.

If these genes are coming from humans, and are already in a given genome, why not take advantage of transposons and proliferate the target genes throughout the genome without introducing anything new? By the same line of thinking, couldn't one just inhibit sequences that encode for factors which inhibit the target genes, resulting in increased expression?

[Moontanman]

Originally Posted by GAHD

A serum should only be taken once, no? Safe to say it would best be a biological agent, perhapse one or many engineered retrovirus' without the ability to create a new vireal sheath to reinfect other cells. (or alternately, don't and make it an ST"D")

something(s) designed to slide in and manipulate the human equivalents of the genes isolated in these experiments:

http://hypography.com/forums/medical...ow-organs.html
"SCIENTISTS have created a “miracle mouse” that can regenerate amputated limbs or badly damaged organs, making it able to recover from injuries that would kill or permanently disable normal animals."

http://hypography.com/forums/news-br...cientists.html
" The mouse can run up to six kilometres at a speed of 20 metres per minute for five hours or more without stopping,"

http://hypography.com/forums/medical...-mightier.html
"these muscular mice averaged a 117 percent increase in muscle fiber size and a 73 percent increase in total muscle fibers compared to normal mice." (seriously, look at the picture!)

They Have isolated the human genes for this last one atleast, the others I'm not so shure. weather they could breed a viri to target those specific parts for dislocation with modern research is another matter.

I'd like to see what the decendants of these 3 lines intermixed would be like!

For comic fan appeal, this would be more akin to the Greay Hulk: That much densely packed muscle offers a certain armor of it's own, but combined with regenerative capabilities, an allbut decapitated person has a chance to recover.

HERE I COME TO SAVE THE DAY! That means that Mighty Mouse is on the way!

[GAHD]

Originally Posted by Alighieri

If these genes are coming from humans, and are already in a given genome, why not take advantage of transposons and proliferate the target genes throughout the genome without introducing anything new?

explain?

[Alighieri]

The human genome is a massive dynamic system where contituents are constantly integrating, excising, and transporting across chromosomes. If these genes exist already in the genome then they have the ability to proliferate through transposition as a mechanism to increase their expression rate. They act as a micro-ecosystem. If they are retroviral in origin they will likely move via retro-transposition but there are other mechanisms if they are not. That being said, there should be a way to stimulate a particular gene to transpose itself to multiple transcription sites. This would result in increased expression of the said gene and the desired effects without introducing any new genes via vectors. All that would be required is chemical stimulation

[JulianKeller]

there should be a way to stimulate a particular gene to transpose itself to multiple transcription sites. This would result in increased expression of the said gene and the desired effects without introducing any new genes via vectors. All that would be required is chemical stimulation

I think that you are saying, (I'm repeating my understanding in my words), that there is possibly a way to turn on the genes for increased muscle mass and metabolic efficiency creating the perfect human specimen right?

If this is true then how would it be done?


This is from an article somewhere online I read

Phyllomedusa bicolor (common names: Giant Monkey Frog; Sapo Mono; Kambo)is a large green noctural frog that lives in the trees of the Peruvian and Brazilian Amazon. Adult frogs secrete a material which is used by the native Mayoruna indians primarily as a hunting aid. The secretion is introduced into the blood stream through small breaks in the skin, after which the active(psychedelic in nature of overall effect) peptides contained in the secretion produce an increase in strength, heightened senses, and resistance to hunger and thirst.

Is there a way to take just the chemicals which enhance strength, senses, resistance to hunger and thirst and make them into a serum which the body reproduces regularly making an increased in strength, heightened sensed, more durable human being?


from another article online.

Mice given resveratrol, a minor component of red wine and other foods, run twice as far on treadmills before collapsing from exhaustion. Normal, non-drugged, abused lab mice run about a kilometer before they collapse from exhaustion. Mice on resveratrol also have reduced heart rates and energy-charged muscles. Resveratrol also expands the lifespan of mice by 30 percent.

Dr. Johan Auwerx, from the Institute of Genetics and Molecular and Cellular Biology in Illkrich, France says that that "Resveratrol makes you look like a trained athlete without the training."

The good doctor also adds that he found that the muscle fibers in the mice had been remodeled by the drug into the type more prevalent in trained human athletes.

Is it possible that if a person regularly took this resveratrol their body would begin to produce it naturally so they could have the benefits of the drug all the time?

Is it possible to somehow "Load Up" a human's system with this drug and over days/weeks/months have them become the peak of human perfection and then have some theoretical way of maintaining it without taking doses of the drug?

[Moontanman]

Mice given resveratrol, a minor component of red wine and other foods, run twice as far on treadmills before collapsing from exhaustion. Normal, non-drugged, abused lab mice run about a kilometer before they collapse from exhaustion. Mice on resveratrol also have reduced heart rates and energy-charged muscles. Resveratrol also expands the lifespan of mice by 30 percent.

Dr. Johan Auwerx, from the Institute of Genetics and Molecular and Cellular Biology in Illkrich, France says that that "Resveratrol makes you look like a trained athlete without the training."

The good doctor also adds that he found that the muscle fibers in the mice had been remodeled by the drug into the type more prevalent in trained human athletes.

I keep hearing all these great things about "Resveratrol" Is it available on the market yet? If so where would i find it? Is a prescription? Can it be prescribed? Fat old men want to know!