Marijuana as Medicine

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Old 08-02-2008
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Re: Marijuana as Medicine

Quote:
Turned-off Cannabinoid Receptor Turns On Colorectal Tumor Growth

ScienceDaily (Aug. 1, 2008) — New preclinical research shows that cannabinoid cell surface receptor CB1 plays a tumor-suppressing role in human colorectal cancer, scientists report in the Aug. 1 edition of the journal Cancer Research.



CB1 is well-established for relieving pain and nausea, elevating mood and stimulating appetite by serving as a docking station for the cannabinoid group of signaling molecules. It now may serve as a new path for cancer prevention or treatment.
Turned-off Cannabinoid Receptor Turns On Colorectal Tumor Growth
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Old 08-02-2008
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Re: Marijuana as Medicine

In the USA to allow MJ to be legal would require the government admit to loosing another war, just ain't gonna happen. I've already been warned by my doc that he will do his best to ruin my life if I test positive even though it helps my chronic pain better then the opiates he allows me to buy.
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Old 08-03-2008
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Re: Marijuana as Medicine

[quote]
Quote:
Medical Marijuana Users Ask For 71 Ounces

SEATTLE -- Many using medical marijuana said the Health Department's current amount of how much can be possessed legally is too little.

Currently, patients can possess 24 ounces in a 60-day period to relieve pain or nausea, but some users say the rule is too restrictive.

"The 24 ounces is low for the most sick in our society. Those that are eating Cannabis for cancer remission, for example, or for the pain associated with it," said medical marijuana user Muraco Kyashna-Tocha.

Patients said 71 ounces is how much someone who is in severe pain would have to eat to get as much active ingredients from the plants as they would from a prescription substitute called Marinol.
us: Medical Marijuana Users Ask For 71 Ounces - UK420
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Old 08-04-2008
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Re: Marijuana as Medicine

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Why Cannabis Stems Inflammation

. . .People not only rate cannabis sativa L. highly because of its intoxicating effects; it has also long been used as a medicinal plant. Although the plant has been scrutinized for years, surprising new aspects keep cropping up. For example, researchers from ETH Zurich and Bonn University examined a component in the plant’s essential oil that until then had largely been ignored and found it to have remarkable phar- macological effects. The findings open up interesting perspectives, especially for the prevention and treatment of inflammations.

Completely different molecule structure

The hemp plant contains over 450 different substances,
Why Cannabis Stems Inflammation
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Old 08-11-2008
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Re: Marijuana as Medicine

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Medicinal Marijuana Effective For Neuropathic Pain In HIV, Study Finds

ScienceDaily (Aug. 7, 2008) — In a double-blind, placebo-controlled clinical trial to assess the impact of smoked medical cannabis, or marijuana, on the neuropathic pain associated with HIV, researchers at the University of California, San Diego School of Medicine found that reported pain relief was greater with cannabis than with a placebo
Medicinal Marijuana Effective For Neuropathic Pain In HIV, Study Finds
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  #196 (permalink)  
Old 08-15-2008
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Re: Marijuana as Medicine

Cannabis Culture Magazine Online

America's Never-ending Prohibition: from Reuters News

It seems only the White House and law enforcement want drug prohibition to continue
by Bernd Debusmann

WASHINGTON - America's alcohol prohibition lasted 13 years, filled the country's prisons, inspired contempt for the law among millions, bred corruption and produced Al Capone. What it did not do was keep Americans from drinking. America's marijuana prohibition drew into its 72nd year this month. It has created a huge underground industry catering to users, helped the U.S. prison population balloon into the world's largest, and diverted the resources of American law enforcement. What it has not done is keep Americans from using marijuana.

On the contrary. Since 1937, the year marijuana was outlawed, its use in the United States has gone up by 4,000 percent, according to the Marijuana Policy Project, a Washington-based lobby group which advocates regulating the drug similar to alcohol. A recent World Health Organization study of marijuana use in 17 countries placed Americans at the top of the list.

The 1920-1933 prohibition on the sale, production and transportation of alcohol is now seen as a dismal failure of social engineering. Will the prohibition on marijuana ever be seen in a similar light?

For the first time in a generation, there is a bill before Congress that would eliminate federal penalties "for the personal use of marijuana by responsible adults." But not even the congressman who introduced the bill, Democrat Barney Frank, sees bright prospects for swift passage. The last time the U.S. Congress dealt with legislation that would have decriminalized marijuana was in 1978, when a bill introduced by Senator Edward Kennedy was passed by the Senate but never got to a vote in the House.

The case for legalizing marijuana, the most widely used drug after alcohol and tobacco, rests on several planks - the most obvious being that prohibition simply hasn't worked despite extraordinarily labor-intensive and costly government efforts. In 2006, the last year for which figures from the Federal Bureau of Investigation are available, 830,000 Americans were arrested on marijuana charges, most of them for possession rather than trafficking.

That works out at a marijuana arrest every 38 seconds. A study last year estimated the cost of these arrests at $10.7 billion.

"This is an enormous waste of law enforcement resources that should be focused on violent and serious crime," says Allen St. Pierre, who heads the National Organization for the Reform of Marijuana Laws (NORML), the marijuana smokers' lobby in Washington. "With alcohol we acknowledge the distinction between use and abuse, and we focus our law enforcement on efforts to stop irresponsible use. We do not arrest or jail responsible drinkers. That should be our policy for marijuana as well."

The Bush administration's drug czar, John Walters, will have none of this. He talks about marijuana in terms reminiscent of the apocalyptic warnings issued by Harry Anslinger, the first head of the Bureau of Narcotics in the 1930s and a driving force behind the 1937 marijuana prohibition. Anslinger deemed marijuana "an addictive drug which induces in its users insanity, criminality and death." Walters often takes issue with "the perception that marijuana is about fun and freedom. It isn't. It's about dependency, disease and dysfunction." (For a vivid portrayal of the dysfunction Walters warns about, see a mock documentary produced for the White House Office of National Drug Policy. It is entitled Stoners in the Mist, a play on the 1988 film on mountain gorillas in the Congo.)

Americans who have admitted smoking marijuana at one point or another but escaped dependency, disease and dysfunction include President George W. Bush, Supreme Court Judge Clarence Thomas, California Governor Arnold Schwarzenegger, New York Mayor Michael Bloomberg, Senator John Kerry, former Speaker of the House Newt Gingrich, former Vice President Al Gore and Barack Obama, the Democratic nominee for next November's presidential election.

Former President Bill Clinton falls into a special category. When he studied in England, away from the long reach of U.S. law, he experimented with marijuana "a time or two," he once told a television interviewer. "I didn't inhale and I didn't try again." Hollywood, conscious of a mass audience that does inhale, has produced a slew of new "stoner" movies this year. The pot-smoking protagonists include an investment banker and a medical student (Harold & Kumar), a psychiatrist (The Wackness), and a process server (Pineapple Express).

But sympathetic portrayals of marijuana use in popular culture do not necessarily translate into faster progress towards legalization. Government anti-drug fighters are serious in their opposition. When Barney Frank, at a news conference to explain the rationale for his bill, was asked what timeline he had in mind, he quipped: "Not soon ... but eventually, you'll see the development of a marijuana futures market." David Murray, the chief scientist in the drug czar's office who had listened to the briefing, was not amused. "It's not funny," he said, "not funny at all."

But not impossible either, in the long run.


- Article from Reuters, August 6th 2008


- You can contact the author at Debusmann@Reuters.com
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Old 08-15-2008
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Re: Marijuana as Medicine

The powers that be in government have been pumping this stuff into each other for so long it's like talking to an echo. One claims lies and propaganda as the truth the other confirms it and tells it back to the first one he confirms it and so on. The public is so often caught in the middle of this echo chamber they either believe it too or don't know what to believe. Even people who know better engage in the Echo chamber discussion to simply avoid being ostracized from the conversation. It never ends......
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Old 3 Weeks Ago
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Re: Marijuana as Medicine

the audio wil be at the site for four weeks. The transcript much longer
Cannabis receptors target for stroke treatment - Science Show - 25 October 2008
Quote:

25 October 2008
Cannabis receptors target for stroke treatment

listen now | download audio

There are 2 types of stroke, one with bleeding, the other with a blood clot in the brain. When a clot blocks blood flow, there is a death of nerve cells. Over the following days and weeks, the immune system brings forth inflammation. The purpose of this is to clear any possible infection. The immune system doesn't differentiate between stroke and brain injury. Treatment is difficult. Drugs are required quickly.

Now, a link has been found with brain receptors for cannabis. One cannabis receptor, CB2 becomes more prevalent in the brain following an injury such as stroke. This may be a drug target for attacking the process of inflammation.

Echinacea, the popular herbal medicine is an immune stimulant. Some compounds have been isolated from echinacea which are similar to some of the body's own cannabonoids. It may some therapeutic effects
Cannabis receptors target for stroke treatment - Science Show - 25 October 2008
Quote:
Robyn Williams: SWhere does Echinacea come into this story?

John Ashton: Echinacea has been around since...North American Indians used to use it for toothache to chew on it, and of course it's been used as a popular herbal medicine, and some people use it as an immune stimulant. And we know it is an immune stimulant because it is in fact contraindicated. People who are taking certain drugs, like HIV drugs, shouldn't take it.
So it's been a mystery why it works or what it does and what are the active chemical ingredients. In just the last few years a group in Switzerland have isolated some compounds from Echinacea which looked very similar in their chemical structure to some of the body's own internal cannabinoids.
These drugs, it turns out, are very selective in their activation of the CB2 receptors.

So you can't get high on Echinacea because it doesn't stimulate the CB1 receptor, but it may have these therapeutic effects that CB2 activation does, and it's already been shown in some pain trials that it does have analgesic effects, and now we're trying to see whether Echinacea compounds will help with neuropathic pain.
The excitement whenever you get a natural compound or a natural product extract like this is it's more straightforward to get through into the clinical development process than a completely new synthetic compound because it has been tried in people in various ways for a long time, so the toxicology safety profile of it is somewhat established and the ethics behind pushing it forward is a little bit easier. So we're quite excited about where that's going.

http://www.abc.net.au/rn/scienceshow...htm#transcript
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