Gene test on kids' sporting skills
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BOULDER, COLORADO: When Donna Campiglia learned recently that a genetic test might be able to determine which sports suit the talents of her 2
½-year-old son, Noah, she instantly said, Where can I get it and how much does it cost?
"I could see how some people might think the test would pigeonhole your child into doing fewer sports or being exposed to fewer things, but I still think it's good to match them with the right activity," Campiglia, 36, said as she watched a toddler class at Boulder Indoor Soccer in which Noah struggled to take direction from the coach between juice and potty breaks. "I think it would prevent a lot of parental frustration," she said.
In health-conscious, sports-oriented Boulder, Atlas Sports Genetics is playing into the obsessions of parents by offering a $149 test that aims to predict a child's natural athletic strengths. The process is simple. Swab inside the child's cheek and along the gums to collect DNA and return it to a lab for analysis of ACTN3, one gene among more than 20,000 in the human genome.
The test's goal is to determine whether a person would be best at speed and power sports like sprinting or football, or endurance sports like distance running, or a combination of the two.
In this era of genetic testing, DNA is being analyzed to determine predispositions to disease, but experts raise serious questions about marketing it as a first step in finding a child's sports niche, which some parents consider the road to a college scholarship or a career as a professional athlete.
Atlas executives acknowledge that their test has limitations but say that it could provide guidelines for placing youngsters in sports. The company is focused on testing children from infancy to about 8 years old because physical tests to gauge future sports performance at that age are, at best, unreliable.
Some experts say ACTN3 testing is in its infancy and virtually useless. Theodore Friedmann, the director of the University of California-San Diego Medical Center's interdepartmental gene therapy program, called it "an opportunity to sell new versions of snake oil".
The study that identified the connection between ACTN3 and elite athletic performance was published in 2003 by researchers primarily based in Australia.
Scientists looked at the gene's combinations, one copy provided by each parent. The R variant of ACTN3 instructs the body to produce a protein, alpha-actinin-3, found specifically in fast-twitch muscles. Those muscles are capable of forceful, quick contractions necessary in speed and power sports. The X variant prevents production of the protein.
http://timesofindia.indiatimes.com/H...ow/3781796.cms
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